Medicine

Ibuprofen linked to male infertility

Ibuprofen linked to male infertility

Within just two weeks, it seems that the testosterone-producing hormones in the subjects became linked to the amount of ibuprofen in their blood. The drop in testosterone can cause testicles to shrink, as well as making it more hard to get someone pregnant.

This could result in a condition only usually seen in smokers and older people. And, while testosterone levels are normal during compensated hypogonadism, it's not a good condition to have.

The study involved 31 men, 14 of which were given a daily dose of 600 milligrams ibuprofen twice a day - the amount commonly consumed by athletes, CBS News reported. It was a randomized control trial, with one group of participants receiving ibuprofen and the others receiving placebo. The scientist tested aspirin, Tylenol and ibuprofen. That number rose to a 23 percent decrease after 44 days.

Young men taking ibuprofen saw a coordination between luteinizing hormones (LH) - those that produce testosterone - and the level of ibuprofen in their bloodstream.

This led, they said, to compensated hypogonadism, a condition linked to reproductive and other health problems normally found in elderly men.




'Concern has been raised over increased male reproductive disorders in the Western world and the disruption of male hormones has been suggested to play a central role.

The adverse effects in the study weren't permanent.

'But the effects on the adult man remain largely unknown.

Ibuprofen is a popular over-the-counter drug used to alleviate pain, fever and inflammation - especially in cases of painful menstrual periods, migraines and rheumatoid arthritis. Long term, it can lead to a more serious condition called overt primary hypogonadism, which is characterized by low testosterone and libido, depressed mood and reduced muscle mass and strength.

As a fun added bonus, previous research has found a link between low testosterone levels and premature death. The consistency of the results, however, as well as the earlier epidemiological results, suggest that there might really be an issue here. A new study says the well-known painkiller could cause fertility issues in males. That works out to three ibuprofen tablets per day if you're taking a typical 200mg/tablet product. Before he stepped down in November 2016 he asked players about their use of over-the-counter painkillers and found that almost half of those who played in the past three World Cups took anti-inflammatory drugs, such as ibuprofen, every day.


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